If you’ve been researching hair loss, you’ve probably come across the term DHT (dihydrotestosterone). It’s often described as the root cause of thinning hair, and while it’s true that DHT plays a key role in male pattern baldness, many women don’t realise it’s also a major factor in female pattern hair loss (FPHL), especially during hormonal transitions like postpartum recovery, perimenopause, or in women with PCOS.
The good news? There are natural ways to help reduce DHT’s impact on your scalp, gently and effectively. In this guide, we’ll unpack what DHT actually is, the evidence behind natural DHT blockers, and which ingredients are supported by science (not hype).
What Is DHT and Why Does It Affect Women?
DHT is a potent form of testosterone produced when the enzyme 5-alpha-reductase converts testosterone into its more active form. In the scalp, DHT binds to receptors in hair follicles and gradually shrinks them. A process known as follicle miniaturisation, leading to thinner, weaker hair.
Although men are more prone to DHT-related hair loss, hormonal shifts can make women just as susceptible. This often happens when oestrogen levels drop or androgen levels rise.
Common triggers include:
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Postpartum recovery, when oestrogen falls rapidly
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Perimenopause and menopause, as hormone balance changes
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PCOS, where androgens are naturally elevated
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Chronic stress, which increases cortisol and disrupts hormonal stability
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Nutritional deficiencies, such as low ferritin or vitamin D
When oestrogen declines, DHT becomes relatively more dominant, shortening the hair growth phase (anagen) and increasing shedding. Natural DHT blockers work by gently interfering with this process, helping preserve follicle health and density without hormonal medication.
The Most Effective Natural DHT Blockers (Evidence-Based)
Not every “DHT blocker” you see on social media works as claimed. These are the ingredients with meaningful, peer-reviewed evidence:
1. Saw Palmetto (Serenoa Serrulata)
The heavyweight of natural DHT blockers. Saw palmetto inhibits 5-alpha-reductase, the same enzyme targeted by finasteride.
A systematic review in Skin Appendage Disorders (Evron et al., 2020) found both topical and oral saw palmetto improved hair density and reduced shedding across multiple clinical trials.
You’ll find it in multi-active formulas like the DSD Exogrow Booster, where it’s paired with exosomes, caffeine, and peptides for broader results.
2. Caffeine
Topical caffeine boosts micro-circulation and can extend the anagen phase of the hair cycle.
In a landmark International Journal of Dermatology study (Fischer et al., 2007), caffeine counteracted testosterone-induced growth suppression in human hair follicles.
Follow-up work in the British Journal of Dermatology (2014) confirmed caffeine’s stimulatory action on keratinocyte energy metabolism and hair-shaft elongation.
3. Pumpkin Seed Oil
A randomised, double-blind, placebo-controlled trial in Evidence-Based Complementary and Alternative Medicine (Cho et al., 2014) showed participants taking pumpkin seed oil saw an average 40 % increase in hair count over 24 weeks.
While most data is in men, its anti-androgen and anti-inflammatory effects make it beneficial for women when used topically.
4. Green Tea Extract (EGCG)
Epigallocatechin gallate mildly inhibits DHT production and provides antioxidant support. It’s particularly effective when combined with caffeine or peptides in scalp serums.
5. Rosemary Extract or Oil
A SkinMED clinical comparison (Panahi et al., 2015) found rosemary oil performed similarly to 2 % minoxidil after six months of use, improving circulation and reducing shedding. Consistency and correct concentration are key.
6. Peppermint Oil
Animal studies indicate peppermint oil increases follicle depth and anagen duration — likely by enhancing blood flow. It’s a helpful complementary ingredient in stimulating scalp tonics.
The takeaway
Multi-pathway formulas like DSD de Luxe’s trichologist-designed treatments that combine saw palmetto, caffeine, peptides, and botanical extracts are markedly more effective than any single ingredient alone.
What Doesn’t Block DHT (Common Myths)
Many “hair growth” products over-promise by claiming DHT-blocking properties they don’t have. Here’s what to know:
- Biotin - Doesn’t influence DHT pathways. Supports keratin formation; helps with breakage, not hormonal loss
- Collagen - No hormonal action. Strengthens hair shaft and scalp elasticity
- Castor Oil - No effect on DHT. Hydrates and adds shine, cosmetic only
- Rice Water - Zero impact on 5-alpha-reductase. Smooths temporarily, but no follicular benefit
These can still improve overall hair condition, they just don’t address the hormonal trigger behind thinning.
Topical vs Oral DHT Blockers
For most women, topical treatments are the safest and most targeted approach. They deliver actives directly to the follicle with minimal systemic absorption.
Oral supplements (e.g. saw palmetto capsules) can work but carry drawbacks:
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Variable quality and absorption
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Possible digestive side effects
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Potential interactions with hormonal medication
If you have PCOS or confirmed androgen excess, discuss oral options with your GP or a trichologist. Otherwise, topicals are an effective first line of defence for postpartum, stress-related, or perimenopausal thinning.
Topical DSD solutions with natural DHT-blocking support:
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Exogrow Booster Exosomes + saw palmetto + caffeine
How to Build a Natural DHT-Blocking Routine
Consistency beats complexity. Layer actives logically for cumulative results:
Morning
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Caffeine shampoo to stimulate blood flow and prolong growth
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Scalp serum with saw palmetto or exosomes (e.g. Exogrow Booster)
Evening
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Leave-on lotion (DSD 3.4.4 Anti-Hair Loss Lotion) for overnight absorption
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2–3-minute scalp massage to aid penetration and circulation
Weekly
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Keratin or collagen mask to reinforce new growth and reduce breakage
Lifestyle Support
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Check ferritin, vitamin D, and thyroid levels
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Eat a protein- and omega-rich diet (fish, eggs, nuts, leafy greens)
- Avoid tight hairstyles and excessive heat styling
The Bottom Line
DHT may be the common thread behind many types of hormonal hair loss, but managing it doesn’t require harsh medication. With science-backed natural blockers, a consistent routine, and attention to nutrition, you can slow shedding and protect your density safely.
At SST UK, we champion trichologist-formulated solutions like DSD de Luxe’s Exogrow Booster and 3.4 Series, which combine saw palmetto, caffeine, peptides, and botanical extracts for a multi-pathway defence against DHT.
👉 Explore SST’s full DHT-blocking range and build a targeted routine for stronger, fuller hair naturally.
